1. Gene
  2. Lpar3 - lysophosphatidic acid receptor 3 Gene

Lpar3 - lysophosphatidic acid receptor 3 Gene

中文名称:溶血磷脂酸受体 3

种属: Mus musculus

同用名: Edg7; lpA3

基因 ID: 65086 | 基因类型: protein coding

关于 Lpar3

Chromosome 3: 145,926,718-145,991,941 forward strand.GRCm39:CM000996.3

This gene has 1 transcript (splice variant), 196 orthologues, 18 paralogues and is associated with 7 phenotypes. Biased expression in kidney adult (RPKM 14.3), testis adult (RPKM 9.9) and 11 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性; G蛋白α-亚基结合活性;和磷脂结合活性。参与基因表达。作用于多个过程的上游或内部,包括气泡组装; MAPK 级联的正调控;侧枝萌发的正调控作用。位于轴突。以多种结构表达,包括消化系统;中枢神经系统;泌尿生殖系统;淋巴系统腺体;和感觉器官。与人类 LPAR3(溶血磷脂酸受体 3)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and phospholipid binding activity. Involved in gene expression. Acts upstream of or within several processes, including bleb assembly; positive regulation of MAPK cascade; and positive regulation of collateral sprouting. Located in axon. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human LPAR3 (lysophosphatidic acid receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Lpar3 基因产物(1)

mRNA Protein Name
NM_022983.4 NP_075359.1 lysophosphatidic acid receptor 3
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
22465231 MGI
acts upstream of or within bleb assembly IGI
IGI: 通过遗传相互作用推断
17135244 MGI
acts upstream of collateral sprouting IMP
IMP: 通过突变表型推断
22465231 MGI
involved in gene expression IMP
IMP: 通过突变表型推断
20864640 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
15755723 MGI
acts upstream of or within positive regulation of collateral sprouting IMP
IMP: 通过突变表型推断
22465231 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
22465231 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Lpar3 蛋白结构

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (30 - 303)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (31 - 57)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (64 - 89)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (101 - 131)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (144 - 162)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (182 - 211)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (231 - 261)

7tmA_LPAR3_Edg7

7tmA_LPAR3_Edg7: cd15343 (271 - 296)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 3

LPA receptor 3

LPA-3

endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 7

lysophosphatidic acid receptor Edg-7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpar3 NCBI NCBI:23566