2. Gene
  3. Sln - sarcolipin Gene

Sln - sarcolipin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2310045A07Rik

基因 ID: 66402 | 基因类型: protein coding

关于 Sln

功能概要

Sarcoplasmic reticulum CA(2+)-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of CA(2+) from the cytosol into the lumen of the sarcoplasmic reticulum in muscle cells. This gene encodes a small proteolipid that regulates several sarcoplasmic reticulum CA(2+)-ATPases. The transmembrane protein interacts with CA(2+)-ATPases and reduces the accumulation of CA(2+) in the sarcoplasmic reticulum without affecting the rate of ATP hydrolysis. [provided by RefSeq, Jul 2008]

Sln 基因产物(1)

mRNA Protein Name
NM_025540.2 NP_079816.1 sarcolipin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
27923914 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of ATPase-coupled calcium transmembrane transporter activity IDA
IDA: 通过直接分析推断
27923914 MGI
acts upstream of or within negative regulation of calcium ion binding IDA
IDA: 通过直接分析推断
27923914 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
22961106 MGI
involved in regulation of ATPase-coupled calcium transmembrane transporter activity IMP
IMP: 通过突变表型推断
21697544 MGI
involved in regulation of relaxation of muscle IMP
IMP: 通过突变表型推断
21697544 MGI
involved in sarcoplasmic reticulum calcium ion transport IMP
IMP: 通过突变表型推断
21697544 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
27923914 MGI
located in sarcoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
26816378 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sarcolipin

相关产品

Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113217 Cholesteryl oleate 99.0% 否
HY-147425A Zerlasiran sodium Inhibitor 95.52% 否
HY-113217S Cholesteryl oleate-d7 ≥99.0% 否
HY-W013122 Cholesteryl n-butyrate 99.75% 否
HY-147425 Zerlasiran Inhibitor / 否
HY-113217S1 Cholesteryl oleate-d7-1 / 否
HY-147278 Manusiran Inhibitor / 否
HY-147278A Manusiran sodium Inhibitor / 否
HY-164390 6′SLN / 否
HY-P11025 TMVP1446 / 否
HY-P11026 DOTA-TMVP1446 / 否
HY-RS13381 SLN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-168392 Propylene glycol monopalmitate / 否
HY-RS17627 Sln Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24087 Sln Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sln NCBI NCBI:6588
Macaca fascicularis Sln NCBI NCBI:102131807
Rattus norvegicus Sln NCBI NCBI:367086
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