2. Gene
  3. Tab1 - TGF-beta activated kinase 1/MAP3K7 binding protein 1 Gene

Tab1 - TGF-beta activated kinase 1/MAP3K7 binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Map3k7ip1; b2b449Clo; 2310012M03Rik

基因 ID: 66513 | 基因类型: protein coding

关于 Tab1

功能概要

Enables kinase activator activity. Acts upstream of or within several processes, including circulatory system development; positive regulation of MAPK cascade; and transforming growth factor beta receptor signaling pathway. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Is expressed in genitourinary system. Orthologous to human TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tab1 基因产物(1)

mRNA Protein Name
NM_025609.3 NP_079885.2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kinase activator activity IMP
IMP: 通过突变表型推断
12464436 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17709393 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within cardiac septum development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within heart morphogenesis IMP
IMP: 通过突变表型推断
12464436 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
12464436 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
12464436 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
12464436 MGI
acts upstream of or within transforming growth factor beta receptor signaling pathway IMP
IMP: 通过突变表型推断
12464436 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

Tak1-binding protein 1

mitogen-activated protein kinase kinase kinase 7-interacting protein 1

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N2435 [8]-Shogaol 99.93% 否
HY-114454 INH14 Inhibitor 98.0% 否
HY-167704 NF023 / 否
HY-RS14133 TAB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19961 Tab1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26463 Tab1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tab1 NCBI NCBI:10454
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