2. Gene
  3. Atp2b1 - ATPase, Ca++ transporting, plasma membrane 1 Gene

Atp2b1 - ATPase, Ca++ transporting, plasma membrane 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pmca1; 2810442I22Rik; E130111D10Rik

基因 ID: 67972 | 基因类型: protein coding

关于 Atp2b1

功能概要

Predicted to enable P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration and PDZ domain binding activity. Involved in several processes, including negative regulation of cytosolic calcium ion concentration; positive regulation of bone mineralization; and regulation of vascular associated smooth muscle contraction. Located in basolateral plasma membrane and immunological synapse. Is integral component of presynaptic membrane and integral component of synaptic vesicle membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human ATP2B1 (ATPase plasma membrane Ca2+ transporting 1). [provided by Alliance of Genome Resources, Apr 2022]

Atp2b1 基因产物(5)

mRNA Protein Name
NM_001359506.1 NP_001346435.1 plasma membrane calcium-transporting ATPase 1 isoform 1
NM_001359507.1 NP_001346436.1 plasma membrane calcium-transporting ATPase 1 isoform 3
NM_001359508.1 NP_001346437.1 plasma membrane calcium-transporting ATPase 1 isoform 3
NM_001359509.1 NP_001346438.1 plasma membrane calcium-transporting ATPase 1 isoform 4
NM_026482.2 NP_080758.1 plasma membrane calcium-transporting ATPase 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16352659 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular calcium ion homeostasis IMP
IMP: 通过突变表型推断
16956963 MGI
involved in negative regulation of cytokine production IMP
IMP: 通过突变表型推断
28827723 MGI
involved in negative regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
22311909 MGI
involved in positive regulation of bone mineralization IMP
IMP: 通过突变表型推断
26392310 MGI
involved in positive regulation of calcium ion transport IMP
IMP: 通过突变表型推断
26392310 MGI
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
22311909 MGI
involved in regulation of cytosolic calcium ion concentration IMP
IMP: 通过突变表型推断
24805951 MGI
involved in regulation of vascular associated smooth muscle contraction IMP
IMP: 通过突变表型推断
24805951 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
23460639 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
19233278 MGI
located in immunological synapse IDA
IDA: 通过直接分析推断
28827723 MGI
is active in photoreceptor ribbon synapse IDA
IDA: 通过直接分析推断
19233278 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
19233278 MGI
located in presynaptic membrane IDA
IDA: 通过直接分析推断
30862855 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
30862855 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

plasma membrane calcium-transporting ATPase 1

plasma membrane calcium ATPase

plasma membrane calcium pump

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01194 ATP2B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20524 Atp2b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27033 Atp2b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp2b1 NCBI NCBI:490
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