2. Gene
  3. Trpm7 - transient receptor potential cation channel, subfamily M, member 7 Gene

Trpm7 - transient receptor potential cation channel, subfamily M, member 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Chak; Ltrpc7; LTrpC-7; Trp-plik

基因 ID: 679906 | 基因类型: protein coding

关于 Trpm7

功能概要

Enables Calcium Channel activity and protein kinase activity. Involved in several processes, including calcium ion transport; cellular magnesium ion homeostasis; and memory. Located in several cellular components, including neuronal cell body; synaptic vesicle membrane; and varicosity. Is integral component of membrane. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis-parkinsonism/dementia complex 1. Orthologous to human TRPM7 (transient receptor potential cation channel subfamily M member 7). [provided by Alliance of Genome Resources, Apr 2022]

Trpm7 基因产物(1)

mRNA Protein Name
NM_053705.2 NP_446157.2 transient receptor potential cation channel subfamily M member 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium channel activity IDA
IDA: 通过直接分析推断
12904301 RGD
enables monoatomic cation channel activity IDA
IDA: 通过直接分析推断
11161216 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11161216 RGD
enables protein kinase activity IDA
IDA: 通过直接分析推断
11161216 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in calcium ion transport IDA
IDA: 通过直接分析推断
12904301 RGD
involved in intracellular magnesium ion homeostasis IMP
IMP: 通过突变表型推断
21487014 RGD
involved in memory IMP
IMP: 通过突变表型推断
19734892 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
19734892 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuronal cell body IDA
IDA: 通过直接分析推断
18395621 RGD
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
17088214 RGD
located in varicosity IDA
IDA: 通过直接分析推断
17088214 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transient receptor potential cation channel subfamily M member 7

long transient receptor potential channel 7

transient receptor potential-phospholipase C-interacting kinase

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101302 Naltriben mesylate 99.65% 否
HY-157227 VPC01091.4 Inhibitor 98.04% 否
HY-168608 TRPM7-IN-1 / 否
HY-RS15117 TRPM7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-133717 Naltriben / 否
HY-149999 Xeniafaraunol A Inhibitor / 否
HY-160509 BTB 06061 Inhibitor / 否
HY-162968 MRTF-A-IN-1 Inhibitor / 否
HY-162969 MRTF-A-IN-2 Inhibitor / 否
HY-168471 AAL-149 Inhibitor / 否
HY-RS17425 Trpm7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23880 Trpm7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trpm7 NCBI NCBI:54822
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