1. Gene
  2. Mbd2 - methyl-CpG binding domain protein 2 Gene

Mbd2 - methyl-CpG binding domain protein 2 Gene

种属: Rattus norvegicus

基因 ID: 680172 | 基因类型: protein coding

关于 Mbd2

功能概要

Enables chromatin binding activity. Involved in several processes, including maternal behavior; positive regulation of chromatin binding activity; and regulation of nucleobase-containing compound metabolic process. Located in chromatin. Used to study choline deficiency disease. Biomarker of choline deficiency disease; transient cerebral ischemia; and visual epilepsy. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbd2 基因产物(1)

mRNA Protein Name
NM_001115025.1 NP_001108497.1 methyl-CpG-binding domain protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
25135974 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to organic cyclic compound IEP
IEP: 通过表达模式推断
25135974 RGD
involved in embryonic organ development IEP
IEP: 通过表达模式推断
12672019 RGD
involved in epigenetic regulation of gene expression IEP
IEP: 通过表达模式推断
20735989 RGD
involved in maternal behavior IEP
IEP: 通过表达模式推断
25135974 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
25135974 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
22109888 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
25135974 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
16702315 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
22109888 RGD
involved in ventricular cardiac muscle tissue development IEP
IEP: 通过表达模式推断
20735989 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
25135974 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

methyl-CpG-binding domain protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mbd2 NCBI NCBI:8932