2. Gene
  3. Steap3 - STEAP family member 3 Gene

Steap3 - STEAP family member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tsap6; pHyde; 1010001D01Rik

基因 ID: 68428 | 基因类型: protein coding

关于 Steap3

功能概要

Enables cupric reductase activity and ferric-chelate reductase (NADPH) activity. Acts upstream of or within exosomal secretion; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and transition metal ion transport. Located in endosome and plasma membrane. Is expressed in several structures, including bone; genitourinary system; liver; nervous system; and white fat. Orthologous to human STEAP3 (STEAP3 metalloreductase). [provided by Alliance of Genome Resources, Apr 2022]

Steap3 基因产物(4)

mRNA Protein Name
NM_001085409.2 NP_001078878.1 metalloreductase STEAP3 isoform b
NM_001379354.1 NP_001366283.1 metalloreductase STEAP3 isoform b
NM_001379355.1 NP_001366284.1 metalloreductase STEAP3 isoform a
NM_133186.4 NP_573449.2 metalloreductase STEAP3 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cupric reductase (NADH) activity IDA
IDA: 通过直接分析推断
16609065 MGI
enables ferric-chelate reductase (NADPH) activity IDA
IDA: 通过直接分析推断
16609065 MGI
enables ferric-chelate reductase (NADPH) activity IMP
IMP: 通过突变表型推断
18955558 MGI
enables ferric-chelate reductase activity IDA
IDA: 通过直接分析推断
16227996 MGI
enables ferric-chelate reductase activity IMP
IMP: 通过突变表型推断
16227996 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
26642240 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within copper ion import IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within copper ion import IMP
IMP: 通过突变表型推断
18955558 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
16227996 MGI
acts upstream of or within exosomal secretion IMP
IMP: 通过突变表型推断
18617898 MGI
acts upstream of or within iron import into cell IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within iron ion import across cell outer membrane IDA
IDA: 通过直接分析推断
16609065 MGI
acts upstream of or within iron ion import across cell outer membrane IMP
IMP: 通过突变表型推断
18955558 MGI
acts upstream of or within iron ion transport IMP
IMP: 通过突变表型推断
16227996 MGI
acts upstream of or within positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: 通过突变表型推断
18617898 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
16227996 MGI
located in endosome membrane IMP
IMP: 通过突变表型推断
18955558 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16227996 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metalloreductase STEAP3

dudulin 2

protein nm1054

six-transmembrane epithelial antigen of prostate 3

tumor suppressor-activated pathway protein 6

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13908 STEAP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17857 Steap3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24326 Steap3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Steap3 NCBI NCBI:55240
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