2. Gene
  3. SETDB1 - Setdb1 SET domain bifurcated histone lysine methyltransferase 1 Gene

SETDB1 - Setdb1 SET domain bifurcated histone lysine methyltransferase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 689883 | 基因类型: protein coding

关于 SETDB1

功能概要

Predicted to enable DNA binding activity; Histone Methyltransferase activity (H3-K9 specific); and promoter-specific chromatin binding activity. Involved in response to ethanol and response to vitamin. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autistic disorder and lung Cancer. Orthologous to human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

SETDB1 基因产物(1)

mRNA Protein Name
NM_001271175.1 NP_001258104.1 histone-lysine N-methyltransferase SETDB1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to ethanol IEP
IEP: 通过表达模式推断
23413810 RGD
involved in response to vitamin IEP
IEP: 通过表达模式推断
23413810 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase SETDB1

SET domain, bifurcated 1

histone-lysine N-methyltransferase SETDB1-like

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-141539 SETDB1-TTD-IN-1 99.93% 否
HY-141539A SETDB1-TTD-IN-1 TFA 99.77% 否
HY-173156 UNC10013 Modulator / 否
HY-168992 UNC6535 Inhibitor / 否
HY-RS12748 SETDB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16697 Setdb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23131 Setdb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens SETDB1 NCBI NCBI:9869
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