2. Gene
  3. Fbxo7 - F-box protein 7 Gene

Fbxo7 - F-box protein 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 2410015K21Rik; A230052G17Rik

基因 ID: 69754 | 基因类型: protein coding

关于 Fbxo7

功能概要

Enables protein kinase binding activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cyclin-dependent protein serine/threonine kinase activity; and negative regulation of lymphocyte differentiation. Located in mitochondrion and nucleus. Is expressed in dorsal root ganglion; gallbladder; liver; trigeminal ganglion; and vagus ganglion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7). [provided by Alliance of Genome Resources, Apr 2022]

Fbxo7 基因产物(3)

mRNA Protein Name
NM_001310745.1 NP_001297674.1 F-box only protein 7 isoform 2
NM_001347151.1 NP_001334080.1 F-box only protein 7 isoform 3
NM_153195.2 NP_694875.2 F-box only protein 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
21652635 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of lymphocyte differentiation IGI
IGI: 通过遗传相互作用推断
21652635 MGI
acts upstream of lymphocyte differentiation IMP
IMP: 通过突变表型推断
21652635 MGI
acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
21652635 MGI
acts upstream of or within negative regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
21652635 MGI
acts upstream of or within negative regulation of lymphocyte differentiation IGI
IGI: 通过遗传相互作用推断
21652635 MGI
acts upstream of or within negative regulation of lymphocyte differentiation IMP
IMP: 通过突变表型推断
21652635 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
26310625 MGI
located in nucleus IDA
IDA: 通过直接分析推断
26310625 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

F-box only protein 7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04813 FBXO7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22503 Fbxo7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29025 Fbxo7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fbxo7 NCBI NCBI:25793
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