2. Gene
  3. Draxin - dorsal inhibitory axon guidance protein Gene

Draxin - dorsal inhibitory axon guidance protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: neucrin; 2610109H07Rik

基因 ID: 70433 | 基因类型: protein coding

关于 Draxin

功能概要

Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of neuron projection development; and nervous system development. Acts upstream of or within negative regulation of axon extension and negative regulation of neuron apoptotic process. Located in extracellular region. Is expressed in several structures, including central nervous system; dorsal root ganglion; future brain; neural retina; and vibrissa. Orthologous to human DRAXIN (dorsal inhibitory axon guidance protein). [provided by Alliance of Genome Resources, Apr 2022]

Draxin 基因产物(1)

mRNA Protein Name
NM_027426.3 NP_081702.2 draxin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19857465 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in anterior commissure morphogenesis IMP
IMP: 通过突变表型推断
23206892 MGI
involved in axon guidance IMP
IMP: 通过突变表型推断
19150847 MGI
involved in commissural neuron differentiation in spinal cord IMP
IMP: 通过突变表型推断
19150847 MGI
involved in dorsal spinal cord development IMP
IMP: 通过突变表型推断
19150847 MGI
involved in forebrain development IMP
IMP: 通过突变表型推断
19150847 MGI
acts upstream of hippocampal neuron apoptotic process IMP
IMP: 通过突变表型推断
19808066 MGI
acts upstream of or within negative regulation of axon extension IDA
IDA: 通过直接分析推断
20621059 MGI
involved in negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
19857465 MGI
acts upstream of or within negative regulation of hippocampal neuron apoptotic process IMP
IMP: 通过突变表型推断
19808066 MGI
involved in negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
23206892 MGI
acts upstream of neuron apoptotic process IMP
IMP: 通过突变表型推断
19808066 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
20621059 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

draxin

dorsal repulsive axon guidance protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03990 DRAXIN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21118 Draxin Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27637 Draxin Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Draxin NCBI NCBI:374946
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