2. Gene
  3. Wdr77 - WD repeat domain 77 Gene

Wdr77 - WD repeat domain 77 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p44/MEP50; 2610003I18Rik; 2610312E17Rik

基因 ID: 70465 | 基因类型: protein coding

关于 Wdr77

功能概要

Predicted to enable methyl-CpG binding activity and nuclear receptor coactivator activity. Acts upstream of or within several processes, including negative regulation of epithelial cell proliferation involved in prostate gland development; regulation of transcription by RNA polymerase II; and secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development. Predicted to be located in Golgi apparatus and nucleus. Predicted to be part of methylosome. Predicted to be active in cytosol; nucleoplasm; and pole plasm. Is expressed in genitourinary system. Orthologous to human WDR77 (WD repeat domain 77). [provided by Alliance of Genome Resources, Apr 2022]

Wdr77 基因产物(1)

mRNA Protein Name
NM_027432.3 NP_081708.1 methylosome protein 50
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23055941 MGI
enables ubiquitin-like ligase-substrate adaptor activity IDA
IDA: 通过直接分析推断
35197566 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of epithelial cell proliferation involved in prostate gland development IMP
IMP: 通过突变表型推断
17032745 MGI
acts upstream of or within negative regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
18356297 MGI
acts upstream of or within negative regulation of epithelial cell proliferation involved in prostate gland development IMP
IMP: 通过突变表型推断
17032745 MGI
acts upstream of or within positive regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
18356297 MGI
involved in protein polyubiquitination IDA
IDA: 通过直接分析推断
35197566 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17032745 MGI
acts upstream of or within secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development IMP
IMP: 通过突变表型推断
17032745 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
35197566 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cul4B-RING E3 ubiquitin ligase complex IDA
IDA: 通过直接分析推断
35197566 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

methylosome protein 50

MEP-50

WD repeat-containing protein 77

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15798 WDR77 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20520 Wdr77 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27029 Wdr77 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wdr77 NCBI NCBI:79084
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z