2. Gene
  3. Spag9 - sperm associated antigen 9 Gene

Spag9 - sperm associated antigen 9 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: JLP; Jip4; syd1; JIP-4; JSAP2; JSAP2a; Mapk8ip4; 3110018C07Rik; 4733401I23Rik; 4831406C20Rik

基因 ID: 70834 | 基因类型: protein coding

关于 Spag9

功能概要

Enables several functions, including MAP-kinase scaffold activity; Kinesin binding activity; and protein kinase binding activity. Acts upstream of or within several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron differentiation. Located in perinuclear region of cytoplasm. Is expressed in central nervous system; dorsal root ganglion; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and liver cirrhosis. Orthologous to human SPAG9 (sperm associated antigen 9). [provided by Alliance of Genome Resources, Apr 2022]

Spag9 基因产物(8)

mRNA Protein Name
NM_001025428.2 NP_001020599.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 2
NM_001025429.2 NP_001020600.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 3
NM_001025430.2 NP_001020601.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 4
NM_001199203.2 NP_001186132.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 5
NM_001199204.2 NP_001186133.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 6
NM_001199205.2 NP_001186134.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 7
NM_001363157.1 NP_001350086.1 C-Jun-amino-terminal kinase-interacting protein 4 isoform 8
NM_027569.3 NP_081845.2 C-Jun-amino-terminal kinase-interacting protein 4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables JUN kinase binding IDA
IDA: 通过直接分析推断
15767678 MGI
enables MAP-kinase scaffold activity IDA
IDA: 通过直接分析推断
15767678 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15767678 MGI
enables kinesin binding IDA
IDA: 通过直接分析推断
15767678 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12391307 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
15767678 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: 通过遗传相互作用推断
15767678 MGI
acts upstream of or within positive regulation of neuron differentiation IMP
IMP: 通过突变表型推断
19244314 MGI
acts upstream of or within striated muscle cell differentiation IGI
IGI: 通过遗传相互作用推断
20160094 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15767678 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

C-Jun-amino-terminal kinase-interacting protein 4

JNK-associated leucine-zipper protein

JNK-interacting leucine zipper

JNK-interacting protein 4

JNK/SAPK-associated protein 2

mitogen-activated protein kinase 8-interacting protein 4

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13627 SPAG9 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22820 Spag9 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29335 Spag9 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spag9 NCBI NCBI:9043
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