2. Gene
  3. Brap - BRCA1 associated protein Gene

Brap - BRCA1 associated protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IMP; BRAP2; 3010002G07Rik

基因 ID: 72399 | 基因类型: protein coding

关于 Brap

功能概要

Predicted to enable identical protein binding activity; nuclear localization sequence binding activity; and ubiquitin protein Ligase activity. Predicted to be involved in negative regulation of signal transduction. Predicted to act upstream of or within MAPK cascade; Ras protein signal transduction; and protein ubiquitination. Predicted to be located in cytosol; nuclear membrane; and nucleoplasm. Predicted to be part of ubiquitin Ligase complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; retina; and vibrissa. Orthologous to human BRAP (BRCA1 associated protein). [provided by Alliance of Genome Resources, Apr 2022]

Brap 基因产物(3)

mRNA Protein Name
NM_001289543.1 NP_001276472.1 BRCA1-associated protein isoform 2
NM_001289544.1 NP_001276473.1 BRCA1-associated protein isoform 3
NM_028227.3 NP_082503.2 BRCA1-associated protein isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25820252 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BRCA1-associated protein

RING-type E3 ubiquitin transferase BRAP2

impedes mitogenic signal propagation

Brap 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Brap Q99MP8 Akap3 Mus musculus O88987
Anti Bait CoIP
25820252
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01591 BRAP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18746 Brap Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25233 Brap Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Brap NCBI NCBI:8315
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