1. Gene
  2. Slc17a7 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 Gene

Slc17a7 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 Gene

种属: Mus musculus

同用名: Vglut1; 2900052E22Rik

基因 ID: 72961 | 基因类型: protein coding

关于 Slc17a7

功能概要

Enables extracellularly glutamate-gated Chloride Channel activity. Involved in neurotransmitter loading into synaptic vesicle. Acts upstream of or within several processes, including chemical synaptic transmission; long-term memory; and sequestering of neurotransmitter. Located in several cellular components, including cerebellar mossy fiber; excitatory synapse; and synaptic vesicle membrane. Is expressed in several structures, including brain; retina layer; and spinal cord dorsal horn. Orthologous to human SLC17A7 (solute carrier family 17 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc17a7 基因产物(1)

mRNA Protein Name
NM_182993.2 NP_892038.2 vesicular glutamate transporter 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-glutamate uniporter activity IDA
IDA: 通过直接分析推断
25433636 MGI
enables chloride channel activity IDA
IDA: 通过直接分析推断
25433636 MGI
enables extracellularly glutamate-gated chloride channel activity IDA
IDA: 通过直接分析推断
19169251 MGI
enables phosphate ion uniporter activity IDA
IDA: 通过直接分析推断
29642010 MGI
enables sodium:phosphate symporter activity IDA
IDA: 通过直接分析推断
29642010 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within L-glutamate import IDA
IDA: 通过直接分析推断
15860731 MGI
acts upstream of or within L-glutamate import IGI
IGI: 通过遗传相互作用推断
15860731 MGI
acts upstream of or within L-glutamate import IMP
IMP: 通过突变表型推断
15118123 MGI
involved in L-glutamate transmembrane transport IDA
IDA: 通过直接分析推断
25433636 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: 通过突变表型推断
17611277 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
15118123 MGI
acts upstream of or within excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
15118123 MGI
acts upstream of or within long-term memory IMP
IMP: 通过突变表型推断
17241289 MGI
acts upstream of or within maintenance of location in cell IMP
IMP: 通过突变表型推断
15103023 MGI
involved in neurotransmitter loading into synaptic vesicle IDA
IDA: 通过直接分析推断
15118123 MGI
involved in neurotransmitter loading into synaptic vesicle IMP
IMP: 通过突变表型推断
15118123 MGI
involved in phosphate ion homeostasis IDA
IDA: 通过直接分析推断
33440152 MGI
involved in phosphate ion transmembrane transport IDA
IDA: 通过直接分析推断
29642010 MGI
involved in phosphate ion transport IDA
IDA: 通过直接分析推断
29642010 MGI
acts upstream of or within sequestering of neurotransmitter IMP
IMP: 通过突变表型推断
15103023 MGI
involved in sodium-dependent phosphate transport IDA
IDA: 通过直接分析推断
29642010 MGI
acts upstream of or within synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
15118123 MGI
acts upstream of or within synaptic vesicle lumen acidification IMP
IMP: 通过突变表型推断
19169251 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cerebellar mossy fiber IDA
IDA: 通过直接分析推断
23791195 MGI
located in excitatory synapse IDA
IDA: 通过直接分析推断
16980967 MGI
located in presynaptic active zone IDA
IDA: 通过直接分析推断
18986540 MGI
located in synapse IDA
IDA: 通过直接分析推断
15118123 MGI
located in synaptic vesicle IDA
IDA: 通过直接分析推断
15579147 MGI
located in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
15860731 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

vesicular glutamate transporter 1

brain-specific Na(+)-dependent inorganic phosphate cotransporter

solute carrier family 17 member 7

Slc17a7 抗体

目录号 产品名 应用 反应物种
HY-P87140 VGluT1 Antibody (YA6833) WB, IHC-P Mouse, Rat
HY-P87141 VGluT1 Antibody (YA6834) WB, IHC-P, IHC-F Mouse, Rat

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc17a7 NCBI NCBI:57030