1. Gene
  2. Pear1 - platelet endothelial aggregation receptor 1 Gene

Pear1 - platelet endothelial aggregation receptor 1 Gene

种属: Mus musculus

同用名: Jedi-1; Megf12; 3110045G13Rik

基因 ID: 73182 | 基因类型: protein coding

关于 Pear1

功能概要

Enables signaling receptor activity. Involved in phosphatidylinositol 3-kinase signaling; platelet aggregation; and protein kinase B signaling. Acts upstream of or within recognition of apoptotic cell. Located in phagocytic cup. Is active in plasma membrane. Is expressed in brain; dorsal root ganglion; embryo; and heart. Orthologous to human PEAR1 (platelet endothelial aggregation receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pear1 基因产物(6)

mRNA Protein Name
NM_001032413.1 NP_001027585.1 platelet endothelial aggregation receptor 1 isoform a precursor
NM_001032414.1 NP_001027586.1 platelet endothelial aggregation receptor 1 isoform a precursor
NM_001289600.1 NP_001276529.1 platelet endothelial aggregation receptor 1 isoform b
NM_001289601.1 NP_001276530.1 platelet endothelial aggregation receptor 1 isoform c
NM_028460.2 NP_082736.1 platelet endothelial aggregation receptor 1 isoform a precursor
NM_152799.2 NP_690012.2 platelet endothelial aggregation receptor 1 isoform a precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables signaling receptor activity IDA
IDA: 通过直接分析推断
27614188 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
27614188 MGI
involved in platelet aggregation IDA
IDA: 通过直接分析推断
27614188 MGI
involved in positive regulation of platelet activation IMP
IMP: 通过突变表型推断
36792666 MGI
acts upstream of or within recognition of apoptotic cell IDA
IDA: 通过直接分析推断
19915564 MGI
acts upstream of or within recognition of apoptotic cell IMP
IMP: 通过突变表型推断
19915564 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in phagocytic cup IDA
IDA: 通过直接分析推断
19915564 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
27614188 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

platelet endothelial aggregation receptor 1

Jedi

jagged and Delta protein

mPEAR1

multiple EGF-like domains protein 12

multiple epidermal growth factor-like domains protein 12

protein Jedi

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pear1 NCBI NCBI:375033
Rattus norvegicus Pear1 NCBI NCBI:295293