2. Gene
  3. UPP1 - uridine phosphorylase 1 Gene

UPP1 - uridine phosphorylase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：尿苷磷酸化酶 1

种属: Homo sapiens

同用名: UP; UPP; UPASE; UDRPASE

基因 ID: 7378 | 基因类型: protein coding

关于 UPP1

Cytogenetic location: 7p12.3 Genomic coordinates (GRCh38): 7:48,088,704-48,108,736 (from NCBI)

This gene has 12 transcripts (splice variants), 229 orthologues and 1 paralogue. Broad expression in bone marrow (RPKM 27.1), esophagus (RPKM 7.4) and 19 other tissues.

功能概要

该基因编码尿苷磷酸化酶，该酶催化尿苷 (或 2'-脱氧尿苷) 可逆磷酸化为尿嘧啶和核糖-1-磷酸 (或脱氧核糖-1-磷酸) 。编码的酶在嘧啶核糖核苷的降解和回收中发挥作用。[RefSeq 提供，2016 年 10 月]

This gene encodes a uridine phosphorylase, an Enzyme that catalyzes the reversible phosphorylation of uridine (or 2'- deoxyuridine) to uracil and ribose-1-phosphate (or deoxyribose-1-phosphate). The encoded Enzyme functions in the degradation and salvage of pyrimidine ribonucleosides. [provided by RefSeq, Oct 2016]

UPP1 基因产物(6)

mRNA Protein Name
NM_001287426.2 NP_001274355.1 uridine phosphorylase 1 isoform a
NM_001287428.2 NP_001274357.1 uridine phosphorylase 1 isoform b
NM_001287429.2 NP_001274358.1 uridine phosphorylase 1 isoform b
NM_001287430.1 NP_001274359.1 uridine phosphorylase 1 isoform b
NM_001362774.2 NP_001349703.1 uridine phosphorylase 1 isoform a
NM_003364.4 NP_003355.1 uridine phosphorylase 1 isoform a

UPP1 蛋白结构

PNP_UDP_1

PNP_UDP_1: Phosphorylase superfamily (55 - 303)

  • 0
  • 100
  • 200
  • 310 a.a.
蛋白主名 其他名称

uridine phosphorylase 1

UPase 1

重组 UPP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71416 UPP1 Protein, Human (His) Q86Y75 (M1-A173) ≥95%

关联疾病

疾病名称 别名
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15490 UPP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus UPP1 VGNC VGNC:36688
Felis catus UPP1 VGNC VGNC:66846
Mus musculus UPP1 MGD MGI:1097668
Rattus norvegicus UPP1 RGD RGD:1305566
Macaca mulatta UPP1 VGNC VGNC:78726
Others UPP1 NCBI
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