1. Gene
  2. Kdm8 - lysine (K)-specific demethylase 8 Gene

Kdm8 - lysine (K)-specific demethylase 8 Gene

种属: Mus musculus

同用名: Jmjd5; 3110005O21Rik

基因 ID: 77035 | 基因类型: protein coding

关于 Kdm8

功能概要

Predicted to enable several functions, including 2-oxoglutarate-dependent dioxygenase activity; methylated histone binding activity; and peptidase activity. Involved in circadian regulation of gene expression and protein destabilization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; genitourinary system; nervous system; and trachea. Orthologous to human KDM8 (lysine demethylase 8). [provided by Alliance of Genome Resources, Apr 2022]

Kdm8 基因产物(1)

mRNA Protein Name
NM_029842.5 NP_084118.1 bifunctional peptidase and arginyl-hydroxylase JMJD5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
26334721 MGI
enables p53 binding IDA
IDA: 通过直接分析推断
26334721 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
30500822 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian regulation of gene expression IMP
IMP: 通过突变表型推断
30500822 MGI
acts upstream of or within fibroblast proliferation IGI
IGI: 通过遗传相互作用推断
26334721 MGI
acts upstream of or within fibroblast proliferation IMP
IMP: 通过突变表型推断
26334721 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
26334721 MGI
involved in protein destabilization IMP
IMP: 通过突变表型推断
30500822 MGI
acts upstream of or within regulation of DNA-binding transcription factor activity IMP
IMP: 通过突变表型推断
26334721 MGI
acts upstream of or within regulation of signal transduction by p53 class mediator IMP
IMP: 通过突变表型推断
26334721 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

bifunctional peptidase and arginyl-hydroxylase JMJD5

L-arginine (3R)-hydroxylase KDM8

arginyl C3-hydroxylase KDM8

jmjC domain-containing protein 5

jumonji C domain-containing protein 5

jumonji domain containing 5

jumonji domain-containing protein 5

lysine-specific demethylase 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm8 NCBI NCBI:79831