2. Gene
  3. Prkaa2 - protein kinase AMP-activated catalytic subunit alpha 2 Gene

Prkaa2 - protein kinase AMP-activated catalytic subunit alpha 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ampk; Ampka2

基因 ID: 78975 | 基因类型: protein coding

关于 Prkaa2

功能概要

Enables AMP-activated protein kinase activity; ATP binding activity; and protein-macromolecule adaptor activity. Involved in several processes, including energy homeostasis; fatty acid homeostasis; and positive regulation of glycolytic process. Located in several cellular components, including apical plasma membrane; dendrite; and neuronal cell body. Part of nucleotide-activated protein kinase complex. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PRKAA2 (protein kinase AMP-activated catalytic subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Prkaa2 基因产物(1)

mRNA Protein Name
NM_023991.1 NP_076481.1 5'-AMP-activated protein kinase catalytic subunit alpha-2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables AMP-activated protein kinase activity IDA
IDA: 通过直接分析推断
11069105 RGD
enables AMP-activated protein kinase activity IMP
IMP: 通过突变表型推断
8955377 RGD
enables ATP binding IDA
IDA: 通过直接分析推断
16648175 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
11069105 RGD
enables protein kinase activity IDA
IDA: 通过直接分析推断
12065578 RGD
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
8955377 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
14511394 RGD
enables protein-macromolecule adaptor activity IDA
IDA: 通过直接分析推断
15695819 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to calcium ion IMP
IMP: 通过突变表型推断
25788287 RGD
involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
25788287 RGD
involved in energy homeostasis IDA
IDA: 通过直接分析推断
11724780 RGD
involved in fatty acid homeostasis IDA
IDA: 通过直接分析推断
11724780 RGD
involved in positive regulation of glycolytic process IDA
IDA: 通过直接分析推断
11069105 RGD
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
8955377 RGD
involved in regulation of lipid metabolic process IDA
IDA: 通过直接分析推断
12065578 RGD
involved in response to activity IDA
IDA: 通过直接分析推断
17253964 RGD
involved in response to caffeine IDA
IDA: 通过直接分析推断
19608206 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18256313 RGD
located in axon IMP
IMP: 通过突变表型推断
25788287 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
18256313 RGD
located in dendrite IMP
IMP: 通过突变表型推断
25788287 RGD
located in neuronal cell body IMP
IMP: 通过突变表型推断
25788287 RGD
part of nucleotide-activated protein kinase complex IDA
IDA: 通过直接分析推断
16648175 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
14511394 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5'-AMP-activated protein kinase catalytic subunit alpha-2

ACACA kinase

AMP-activated protein kinase

AMPK alpha-2 chain

AMPK subunit alpha-2

HMGCR kinase

acetyl-CoA carboxylase kinase

hydroxymethylglutaryl-CoA reductase kinase

protein kinase, AMP-activated, alpha 2 catalytic subunit

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11101 PRKAA2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21177 Prkaa2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27694 Prkaa2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prkaa2 NCBI NCBI:5563
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