2. Gene
  3. HROB - homologous recombination factor with OB-fold Gene

HROB - homologous recombination factor with OB-fold Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：OB 折叠同源重组因子

种属: Homo sapiens

同用名: MCM8IP; C17orf53

基因 ID: 78995 | 基因类型: protein coding

关于 HROB

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,141,930-44,162,476 (from NCBI)

This gene has 5 transcripts (splice variants) and 188 orthologues. Broad expression in testis (RPKM 4.5), bone marrow (RPKM 2.8) and 14 other tissues.

功能概要

预测可实现单链 DNA 结合活性。参与 DNA 合成，参与 DNA 修复和链间交联修复。位于 DNA 损伤部位。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable single-stranded DNA binding activity. Involved in DNA synthesis involved in DNA repair and interstrand cross-link repair. Located in site of DNA damage. [provided by Alliance of Genome Resources, Apr 2022]

HROB 基因产物(4)

mRNA Protein Name
NM_001171251.3 NP_001164722.1 homologous recombination OB-fold protein isoform 2
NM_001321310.2 NP_001308239.1 homologous recombination OB-fold protein isoform 3
NM_001321311.2 NP_001308240.1 homologous recombination OB-fold protein isoform 4
NM_024032.5 NP_076937.2 homologous recombination OB-fold protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31467087 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in DNA damage response IMP
IMP: 通过突变表型推断
31467087 GOA
involved in DNA synthesis involved in DNA repair IMP
IMP: 通过突变表型推断
31467087 GOA
involved in interstrand cross-link repair IMP
IMP: 通过突变表型推断
31467087 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in site of DNA damage IMP
IMP: 通过突变表型推断
31467087 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

homologous recombination OB-fold protein

MCM8-9-Interacting Protein)

HROB 抗体

目录号 产品名 应用 反应物种
HY-P84670 C17ORF53 Antibody (YA4367) ICC/IF, FC, ELISA Human

关联疾病

疾病名称 别名
Premature Menopause

Primary Ovarian Insufficiency

Premature Ovarian Failure

Hypergonadotropic Hypogonadism

Premature Ovarian Insufficiency

Menopause - Premature

Menopause Praecox

Menopause Premature

Menopause, Premature

Female Hypergonadotropic Hypogonadism

Hypergonadotrophic Ovarian Failure

Primary Female Hypogonadism

Pof - [Premature Ovarian Failure]

Ovarian Failure

Ovarian Secretion Suppression

Ovary Hyposecretion

Ovary Secretion Deficiency

Premature Menopause Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06373 HROB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17246 Hrob Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23700 Hrob Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta HROB VGNC VGNC:70421
Bos taurus HROB VGNC VGNC:52654
Felis catus HROB VGNC VGNC:60725
Rattus norvegicus HROB RGD RGD:1305385
Canis familiaris HROB VGNC VGNC:49206
Mus musculus HROB MGD MGI:2387601
Others HROB NCBI
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