1. Gene
  2. Cxcr6 - chemokine (C-X-C motif) receptor 6 Gene

Cxcr6 - chemokine (C-X-C motif) receptor 6 Gene

中文名称:趋化因子 (CXC 基序) 受体 6

种属: Mus musculus

同用名: BONZO; STRL33

基因 ID: 80901 | 基因类型: protein coding

关于 Cxcr6

Chromosome 9: 123,635,540-123,640,825 forward strand.GRCm39:CM001002.3

This gene has 2 transcripts (splice variants), 97 orthologues, 25 paralogues and is associated with 2 phenotypes. Biased expression in mammary gland adult (RPKM 2.4), spleen adult (RPKM 2.2) and 14 other tissues.

功能概要

该基因编码的蛋白可启动 CXC 趋化因子结合活性和 CXC 趋化因子受体活性。预计参与多个过程,包括钙介导的信号传导;细胞趋化性;和细胞溶质钙离子浓度的正调节。预测作用于信号转导的上游或内部。预测位于质膜中。预计是膜的组成部分。预计在质膜外侧活跃。在中枢神经系统和视网膜中表达。与人 CXCR6(CXC 基序趋化因子受体 6)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables C-X-C chemokine binding activity and C-X-C Chemokine Receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human CXCR6 (C-X-C motif Chemokine Receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Cxcr6 基因产物(1)

mRNA Protein Name
NM_030712.4 NP_109637.3 C-X-C chemokine receptor type 6
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables C-X-C chemokine binding IPI
IPI: 通过物理相互作用推断
11017100 MGI
enables C-X-C chemokine receptor activity IDA
IDA: 通过直接分析推断
11017100 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Cxcr6 蛋白结构

7tmA_CXCR6

7tmA_CXCR6: cd15173 (40 - 306)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (40 - 67)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (74 - 99)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (110 - 140)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (154 - 176)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (196 - 225)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (232 - 262)

7tmA_CXCR6

7tmA_CXCR6: cd15173 (275 - 300)

  • 0
  • 100
  • 200
  • 300
  • 351 a.a.
蛋白主名 其他名称

C-X-C chemokine receptor type 6

CXC-R6

CXCR-6

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcr6 NCBI NCBI:10663