2. Gene
  3. Ogg1 - 8-oxoguanine DNA glycosylase Gene

Ogg1 - 8-oxoguanine DNA glycosylase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81528 | 基因类型: protein coding

关于 Ogg1

功能概要

Enables damaged DNA binding activity and oxidized purine nucleobase lesion DNA N-glycosylase activity. Involved in several processes, including cellular response to cadmium ion; response to estradiol; and response to folic acid. Located in mitochondrion and nucleus. Biomarker of hepatitis; middle cerebral artery infarction; renal cell carcinoma; status epilepticus; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in several diseases, including Graves' disease; angiomyolipoma; carcinoma (multiple); eye disease (multiple); and reproductive organ Cancer (multiple). Orthologous to human OGG1 (8-oxoguanine DNA glycosylase). [provided by Alliance of Genome Resources, Apr 2022]

Ogg1 基因产物(1)

mRNA Protein Name
NM_030870.1 NP_110497.1 N-glycosylase/DNA lyase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA N-glycosylase activity IDA
IDA: 通过直接分析推断
9801319 RGD
enables damaged DNA binding IDA
IDA: 通过直接分析推断
9801319 RGD
enables oxidized purine nucleobase lesion DNA N-glycosylase activity IDA
IDA: 通过直接分析推断
9801319 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in base-excision repair IDA
IDA: 通过直接分析推断
9801319 RGD
involved in cellular response to cadmium ion IEP
IEP: 通过表达模式推断
12499121 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
20969951 RGD
involved in response to estradiol IDA
IDA: 通过直接分析推断
16182450 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
11524300 RGD
involved in response to folic acid IEP
IEP: 通过表达模式推断
20051376 RGD
involved in response to light stimulus IEP
IEP: 通过表达模式推断
15979612 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11872643 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

N-glycosylase/DNA lyase

8-oxoguanine DNA-glycosylase 1

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125276 TH5487 Inhibitor 98.76% 否
HY-147313 TH10785 Activator 99.93% 否
HY-112902 OGG1-IN-08 Inhibitor 99.60% 否
HY-139056 SU0268 Inhibitor 99.96% 否
HY-179014 OGG1 activator-1 Activator / 否
HY-RS09763 OGG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23196 Ogg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ogg1 NCBI NCBI:4968
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z