2. Gene
  3. Thra - thyroid hormone receptor alpha Gene

Thra - thyroid hormone receptor alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ERBA1; Thra1; c-erbA-1

基因 ID: 81812 | 基因类型: protein coding

关于 Thra

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; nucleic acid binding activity; and protein homodimerization activity. Involved in several processes, including animal organ development; digestive tract development; and regulation of transcription, DNA-templated. Located in cytosol; mitochondrion; and nucleus. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 6 and renal cell carcinoma. Orthologous to human THRA (Thyroid Hormone Receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Thra 基因产物(2)

mRNA Protein Name
NM_001017960.2 NP_001017960.1 thyroid hormone receptor alpha isoform TRalpha1
NM_031134.2 NP_112396.2 c-erbAalpha2 isoform TRalpha2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
12039959 RGD
enables intronic transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
20368265 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20078863 RGD
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
8407924 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
8407924 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8407924 RGD
enables single-stranded RNA binding IDA
IDA: 通过直接分析推断
16356627 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adrenal gland development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in digestive tract development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in embryonic organ development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in liver development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in lung development IEP
IEP: 通过表达模式推断
17496154 RGD
involved in negative regulation of DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
2537467 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12039959 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19794517 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18930353 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thyroid hormone receptor alpha

c-erbAalpha2

C-erbA-alpha

avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 1

c-erb-A thyroid hormone receptor

c-erbA-alpha2

nuclear receptor subfamily 1 group A member 1

thyroid hormone receptor alpha 1 (avian erythroblastic leukemia viral (v-erb-a)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14499 THRA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17595 Thra Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24055 Thra Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Thra NCBI NCBI:7067
Mus musculus Thra NCBI NCBI:21833
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z