2. Gene
  3. Lrp4 - LDL receptor related protein 4 Gene

Lrp4 - LDL receptor related protein 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Megf7

基因 ID: 83469 | 基因类型: protein coding

关于 Lrp4

功能概要

Enables Apolipoprotein binding activity; receptor tyrosine kinase binding activity; and scaffold protein binding activity. Involved in dendrite morphogenesis and synapse organization. Located in several cellular components, including neuronal cell body; plasma membrane raft; and postsynaptic density. Human ortholog(s) of this gene implicated in Cenani-Lenz syndactyly syndrome; congenital myasthenic syndrome 17; and sclerosteosis 2. Orthologous to human LRP4 (LDL receptor related protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Lrp4 基因产物(1)

mRNA Protein Name
NM_031322.3 NP_112612.2 low-density lipoprotein receptor-related protein 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables apolipoprotein binding IPI
IPI: 通过物理相互作用推断
17889837 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
18957220 RGD
enables receptor tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
18957220 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
16819975 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
17889837 RGD
involved in synapse organization IMP
IMP: 通过突变表型推断
17889837 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
16819975 RGD
located in dendrite IDA
IDA: 通过直接分析推断
16819975 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
16819975 RGD
located in plasma membrane raft IDA
IDA: 通过直接分析推断
17889837 RGD
located in postsynaptic density IDA
IDA: 通过直接分析推断
16819975 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
16819975 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

low-density lipoprotein receptor-related protein 4

LRP-4

multiple epidermal growth factor-like domains 7

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03047 CORIN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07799 LRP4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17975 Corin Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19911 Lrp4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26412 Lrp4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lrp4 NCBI NCBI:4038
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