1. Gene
  2. Slc6a2 - solute carrier family 6 member 2 Gene

Slc6a2 - solute carrier family 6 member 2 Gene

种属: Rattus norvegicus

同用名: Net

基因 ID: 83511 | 基因类型: protein coding

关于 Slc6a2

功能概要

Enables alpha-tubulin binding activity; beta-tubulin binding activity; and norepinephrine:sodium symporter activity. Involved in norepinephrine transport and response to xenobiotic stimulus. Located in several cellular components, including cell surface; membrane raft; and neuron projection. Biomarker of mental depression. Human ortholog(s) of this gene implicated in hypertension and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a2 基因产物(1)

mRNA Protein Name
NM_031343.2 NP_112633.2 sodium-dependent noradrenaline transporter
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-tubulin binding IDA
IDA: 通过直接分析推断
18800064 RGD
enables beta-tubulin binding IDA
IDA: 通过直接分析推断
18800064 RGD
enables norepinephrine:sodium symporter activity IDA
IDA: 通过直接分析推断
10196144 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
18800064 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in norepinephrine transport IDA
IDA: 通过直接分析推断
10196144 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18800064 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
14976208 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
10753308 RGD
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
10753308 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sodium-dependent noradrenaline transporter

NaCl-dependent norepinephrine transporter

neurotransmitter transporter, noradrenal

norepinephrine transporter

solute carrier family 6 (neurotransmitter transporter), member 2

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc6a2 NCBI NCBI:6530