2. Gene
  3. Hes7 - hes family bHLH transcription factor 7 Gene

Hes7 - hes family bHLH transcription factor 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: bHLHb37

基因 ID: 84653 | 基因类型: protein coding

关于 Hes7

功能概要

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; post-anal tail morphogenesis; and somitogenesis. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; retina; small intestine; unsegmented mesenchyme; and urinary system. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human HES7 (hes family bHLH transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Hes7 基因产物(2)

mRNA Protein Name
NM_001401507.1 NP_001388436.1 transcription factor HES-7 isoform 2
NM_033041.5 NP_149030.2 transcription factor HES-7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16342160 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IDA
IDA: 通过直接分析推断
11260262 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12783854 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
18775957 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11260262 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
21750544 MGI
acts upstream of or within post-anal tail morphogenesis IMP
IMP: 通过突变表型推断
11641270 MGI
acts upstream of or within rhythmic process IDA
IDA: 通过直接分析推断
11641270 MGI
acts upstream of or within rhythmic process IMP
IMP: 通过突变表型推断
15170214 MGI
acts upstream of or within skeletal system development IMP
IMP: 通过突变表型推断
11641270 MGI
acts upstream of or within somitogenesis IMP
IMP: 通过突变表型推断
11641270 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor HES-7

bHLH factor Hes7

hairy and enhancer of split 7

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-125130 Hesperetin 7-O-glucoside Inhibitor 98.66% 否
HY-RS06140 HES7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22199 Hes7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28721 Hes7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hes7 NCBI NCBI:84667
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