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  2. DNAJC14 - DnaJ heat shock protein family (Hsp40) member C14 Gene

DNAJC14 - DnaJ heat shock protein family (Hsp40) member C14 Gene

中文名称:DnaJ 热休克蛋白家族 (Hsp40) 成员 C14

种属: Homo sapiens

同用名: DNAJ; HDJ3; LIP6; DRIP78

基因 ID: 85406 | 基因类型: protein coding

关于 DNAJC14

Cytogenetic location: 12q13.2 Genomic coordinates (GRCh38): 12:55,820,985-55,830,775 (from NCBI)

This gene has 5 transcripts (splice variants), 226 orthologues and 20 paralogues. Ubiquitous expression in testis (RPKM 16.8), thyroid (RPKM 12.6) and 25 other tissues.

功能概要

预计参与蛋白质运输。位于膜内。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in protein transport. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

DNAJC14 基因产物(5)

mRNA Protein Name
NM_001394687.1 NP_001381616.1 dnaJ homolog subfamily C member 14 isoform 1
NM_001394688.1 NP_001381617.1 dnaJ homolog subfamily C member 14 isoform 1
NM_001394689.1 NP_001381618.1 dnaJ homolog subfamily C member 14 isoform 1
NM_001394690.1 NP_001381619.1 dnaJ homolog subfamily C member 14 isoform 2
NM_032364.6 NP_115740.5 dnaJ homolog subfamily C member 14 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DNAJC14 蛋白结构

DnaJ

DnaJ: DnaJ domain (443 - 504)

Jiv90

Jiv90: Cleavage inducing molecular chaperone (530 - 621)

  • 0
  • 200
  • 400
  • 600
  • 702 a.a.
蛋白主名 其他名称

dnaJ homolog subfamily C member 14

DnaJ (Hsp40) homolog, subfamily C, member 14

DNAJC14 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DNAJC14 Q6Y2X3 SARNP Homo sapiens P82979 33961781
种属内
DNAJC14 Q6Y2X3 SARNP Homo sapiens P82979 28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Yellow Fever

Urban Yellow Fever

Jungle Yellow Fever

Sylvatic Yellow Fever

Yf

Yellow Fever, Sylvan

Bronze John

Yellow Jack

Yf- [Yellow Fever]

Febris Flava

Deafness, Autosomal Recessive 4, With Enlarged Vestibular Aqueduct

Enlarged Vestibular Aqueduct

DFNB4

Neurosensory Nonsyndromic Recessive Deafness 4

Enlarged Vestibular Aqueduct Syndrome

Nsrd4

Autosomal Recessive Nonsyndromic Deafness 4

Dilated Vestibular Aqueduct

Dva

Enlarged Vestibular Aqueduct, Digenic

Autosomal Recessive Deafness 4 With Enlarged Vestibular Aqueduct

Large Vestibular Aqueduct Syndrome

Deafness, Autosomal Recessive, 4

Deafness Neurosensory Autosomal Recessive 4

Eva

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 4

Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 4

Deafness, Autosomal Recessive, Type 4 , With Enlarged Vestibular Aqueduct

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Familial Glucocorticoid Deficiency

Glucocorticoid Deficiency

Acth Resistance

Adrenal Unresponsiveness To Acth

Hereditary Unresponsiveness To Adrenocorticotropic Hormone

Isolated Glucocorticoid Deficiency

Glucocorticoid Deficiency, Familial

Glucocorticoid Deficiency 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DNAJC14 RGD RGD:620489
Canis familiaris DNAJC14 VGNC VGNC:108204
Mus musculus DNAJC14 MGD MGI:1921580