RGS11 - regulator of G protein signaling 11 Gene

中文名称：G 蛋白信号调节器 11

种属: Homo sapiens

同用名: RS11

关于 RGS11

功能概要

该基因编码的蛋白质属于 RGS (G 蛋白信号调节因子) 家族。 RGS 家族成员在异源三聚体信号转导 G 蛋白的 α 亚基上充当 GTP 酶激活蛋白。这种蛋白质通过增加 G 蛋白 α 亚基的 GTP 酶活性来抑制信号转导，从而使它们进入无活性的 GDP 结合形式。选择性剪接发生在该位点，并且已鉴定出编码不同亚型的四种转录物变体。[RefSeq 提供，2013 年 11 月]

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]