1. Gene
  2. SERPINB12 - serpin family B member 12 Gene

SERPINB12 - serpin family B member 12 Gene

中文名称:serpin 家族 B 成员 12

种属: Homo sapiens

同用名: YUKOPIN

基因 ID: 89777 | 基因类型: protein coding

关于 SERPINB12

Cytogenetic location: 18q21.33 Genomic coordinates (GRCh38): 18:63,519,110-63,569,329 (from NCBI)

This gene has 3 transcripts (splice variants), 90 orthologues and 36 paralogues. Restricted expression toward skin (RPKM 27.9).

功能概要

启用丝氨酸型内肽酶抑制剂活性。预测参与内肽酶活性的负调节。预测作用于造血祖细胞分化的上游或内部。含有胶原蛋白的细胞外基质的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Part of collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

SERPINB12 基因产物(2)

mRNA Protein Name
NM_001307928.2 NP_001294857.1 serpin B12 isoform 1
NM_080474.2 NP_536722.1 serpin B12 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables serine-type endopeptidase inhibitor activity IMP
IMP: 通过突变表型推断
11604408 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SERPINB12 蛋白结构

Serpin

Serpin: Serpin (serine protease inhibitor) (7 - 405)

  • 0
  • 100
  • 200
  • 300
  • 405 a.a.
蛋白主名 其他名称

serpin B12

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12

重组 SERPINB12 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71304 Serpin B12 Protein, Human (HEK293, His) Q96P63-2 (M1-P425) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SERPINB12 RGD RGD:1566382
Felis catus SERPINB12 VGNC VGNC:80485
Macaca mulatta SERPINB12 VGNC VGNC:77231
Mus musculus SERPINB12 MGD MGI:1919119
Canis familiaris SERPINB12 VGNC VGNC:46028
Bos taurus SERPINB12 VGNC VGNC:34471
Others SERPINB12 NCBI