2. Gene
  3. Angpt2 - angiopoietin 2 Gene

Angpt2 - angiopoietin 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Agpt2; Ang-2

基因 ID: 89805 | 基因类型: protein coding

关于 Angpt2

功能概要

Predicted to enable receptor tyrosine kinase binding activity. Involved in several processes, including blood vessel development; maternal process involved in female pregnancy; and positive regulation of angiogenesis. Located in several cellular components, including extracellular space; nucleus; and plasma membrane. Used to study several diseases, including ischemia (multiple); membranoproliferative glomerulonephritis; portal hypertension; retinal disease (multiple); and uremia. Biomarker of several diseases, including Caroli disease; artery disease (multiple); glomerulonephritis (multiple); musculoskeletal system Cancer (multiple); and retinal disease (multiple). Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human ANGPT2 (angiopoietin 2). [provided by Alliance of Genome Resources, Apr 2022]

Angpt2 基因产物(1)

mRNA Protein Name
NM_134454.1 NP_604449.1 angiopoietin-2 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in angiogenesis IEP
IEP: 通过表达模式推断
16439712 RGD
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
16437624 RGD
involved in cellular response to growth factor stimulus IEP
IEP: 通过表达模式推断
16176970 RGD
involved in germ cell development IEP
IEP: 通过表达模式推断
18996974 RGD
involved in glomerulus vasculature development IMP
IMP: 通过突变表型推断
20056745 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
16452728 RGD
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
15542434 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
18342145 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
15048134 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
17943991 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
19012730 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19672036 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
18272601 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16628643 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

angiopoietin-2

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990689 Zifibancimig 99.00% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00688 ANGPT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16719 Angpt2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23155 Angpt2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Angpt2 NCBI NCBI:285
Canis familiaris Angpt2 NCBI NCBI:607616
Macaca fascicularis Angpt2 NCBI NCBI:101925495
Canis lupus familiaris Angpt2 NCBI
Mus musculus Angpt2 NCBI NCBI:11601
Macaca mulatta Angpt2 NCBI NCBI:716811
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