2. Gene
  3. Ptch1 - patched 1 Gene

Ptch1 - patched 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ptch; Ptch2

基因 ID: 89830 | 基因类型: protein coding

关于 Ptch1

功能概要

Predicted to enable several functions, including Cholesterol binding activity; cyclin binding activity; and signaling receptor binding activity. Involved in several processes, including commissural neuron axon guidance; gland development; and response to estradiol. Located in growth cone; nucleus; and postsynaptic density. Human ortholog(s) of this gene implicated in basal cell carcinoma; holoprosencephaly; holoprosencephaly 7; and nevoid basal cell carcinoma syndrome. Orthologous to human PTCH1 (patched 1). [provided by Alliance of Genome Resources, Apr 2022]

Ptch1 基因产物(2)

mRNA Protein Name
NM_001389256.1 NP_001376185.1 protein patched homolog 1 isoform 2
NM_053566.3 NP_446018.1 protein patched homolog 1 isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in commissural neuron axon guidance IMP
IMP: 通过突变表型推断
19946319 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
22024090 RGD
involved in prostate gland development IEP
IEP: 通过表达模式推断
15328011 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
17109907 RGD
involved in response to mechanical stimulus IEP
IEP: 通过表达模式推断
16943241 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18772241 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
17307727 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18772241 RGD
involved in spermatid development IEP
IEP: 通过表达模式推断
21893610 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axonal growth cone IDA
IDA: 通过直接分析推断
21618238 RGD
located in dendritic growth cone IDA
IDA: 通过直接分析推断
21618238 RGD
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
21618238 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein patched homolog 1

patched homolog 2

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W019996 Triparanol 98.21% 否
HY-P10875 HL2-m5 Inhibitor 98.06% 否
HY-137567 Prostaglandin E1 ethanolamide Activator / 否
HY-153499 SMO-IN-4 Antagonist / 否
HY-RS11356 PTCH1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18678 Ptch1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25164 Ptch1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptch1 NCBI NCBI:5727
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