2. Gene
  3. CDKL2 - cyclin dependent kinase like 2 Gene

CDKL2 - cyclin dependent kinase like 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞周期蛋白依赖性激酶样 2

种属: Homo sapiens

同用名: P56; KKIAMRE

基因 ID: 8999 | 基因类型: protein coding

关于 CDKL2

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:75,576,496-75,630,528 (from NCBI)

This gene has 4 transcripts (splice variants), 149 orthologues and 26 paralogues. Biased expression in testis (RPKM 7.0), brain (RPKM 3.3) and 6 other tissues.

功能概要

该基因产物是 CDC2 相关丝氨酸/苏氨酸蛋白激酶大家族的成员。它主要在细胞质中积累，在细胞核中含量较低。[RefSeq 提供，2008 年 7 月]

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus. [provided by RefSeq, Jul 2008]

CDKL2 基因产物(2)

mRNA Protein Name
NM_001330724.2 NP_001317653.1 cyclin-dependent kinase-like 2 isoform 2
NM_003948.5 NP_003939.1 cyclin-dependent kinase-like 2 isoform 1

CDKL2 蛋白结构

Pkinase

Pkinase: Protein kinase domain (4 - 287)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
蛋白主名 其他名称

cyclin-dependent kinase-like 2

CDC2-related kinase

重组 CDKL2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76247 CDKL2 Protein, Human (sf9, His) Q92772 (M1-H493) ≥95%

关联疾病

疾病名称 别名
Meckel Syndrome, Type 4

Meckel Syndrome 4

MKS4

Meckel-Gruber Syndrome, Type 4

Meckel Syndrome Type 4
Orofaciodigital Syndrome Vi

OFD6

Varadi-Papp Syndrome

Varadi Syndrome

Joubert Syndrome With Orofaciodigital Defect

Orofaciodigital Syndrome Type 6

Orofaciodigital Syndrome 6

Oral-Facial-Digital Syndrome, Type Vi

Ofds Vi

Polydactyly, Cleft Lip/Palate Or Lingual Lump, And Psychomotor Retardation

Polydactyly Cleft Lip Palate Psychomotor Retardation

Oral-Facial-Digital Syndrome Type 6

Polydactyly-Cleft Lip/Palate-Psychomotor Retardation Syndrome

Polydactyly - Cleft Lip/Palate - Psychomotor Retardation

Váradi Syndrome

Váradi-Papp Syndrome

Joubert Syndrome With Oral-Facial-Digital Syndrome

Oral-Facial-Digital Syndrome 6

Joubert-Orofaciodigital Syndrome

Orofaciodigital Syndrome, Type Vi
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02406 CDKL2 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CDKL2 VGNC VGNC:27139
Macaca mulatta CDKL2 VGNC VGNC:70987
Mus musculus CDKL2 MGD MGI:1858227
Felis catus CDKL2 VGNC VGNC:60709
Rattus norvegicus CDKL2 RGD RGD:1309625
Canis familiaris CDKL2 VGNC VGNC:39065
Others CDKL2 NCBI
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