2. Gene
  3. Arid1a - AT rich interactive domain 1A (SWI-like) Gene

Arid1a - AT rich interactive domain 1A (SWI-like) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Osa1; BAF250; BAF250a; Smarcf1; 1110030E03Rik

基因 ID: 93760 | 基因类型: protein coding

关于 Arid1a

功能概要

Enables ATP-dependent chromatin remodeler activity. Contributes to nucleosome binding activity. Acts upstream of or within several processes, including animal organ development; embryonic morphogenesis; and toxin transport. Located in chromatin. Part of SWI/SNF complex; nBAF complex; and npBAF complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Coffin-Siris syndrome. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 2; breast cancer; carcinoma (multiple); gastrointestinal system Cancer (multiple); and neuroblastoma. Orthologous to human ARID1A (AT-rich interaction domain 1A). [provided by Alliance of Genome Resources, Apr 2022]

Arid1a 基因产物(6)

mRNA Protein Name
NM_001080819.2 NP_001074288.1 AT-rich interactive domain-containing protein 1A isoform 1
NM_001363070.2 NP_001349999.1 AT-rich interactive domain-containing protein 1A isoform 2
NM_001401271.1 NP_001388200.1 AT-rich interactive domain-containing protein 1A isoform 3
NM_001401273.1 NP_001388202.1 AT-rich interactive domain-containing protein 1A isoform 4
NM_001401275.1 NP_001388204.1 AT-rich interactive domain-containing protein 1A isoform 2
NM_001401276.1 NP_001388205.1 AT-rich interactive domain-containing protein 1A isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP-dependent chromatin remodeler activity IDA
IDA: 通过直接分析推断
23129809 MGI
contributes to nucleosome binding IDA
IDA: 通过直接分析推断
23129809 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11988099 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cardiac chamber development IMP
IMP: 通过突变表型推断
23129809 MGI
acts upstream of or within cardiac muscle cell differentiation IMP
IMP: 通过突变表型推断
24335282 MGI
acts upstream of or within chromatin organization IPI
IPI: 通过物理相互作用推断
11318604 MGI
acts upstream of or within chromatin remodeling IMP
IMP: 通过突变表型推断
18448678 MGI
acts upstream of or within embryo implantation IMP
IMP: 通过突变表型推断
18448678 MGI
acts upstream of or within forebrain development IMP
IMP: 通过突变表型推断
23129809 MGI
acts upstream of or within formation of primary germ layer IMP
IMP: 通过突变表型推断
18448678 MGI
acts upstream of or within gastrulation IMP
IMP: 通过突变表型推断
18448678 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23129809 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
24335282 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
23129809 MGI
acts upstream of or within optic cup formation involved in camera-type eye development IMP
IMP: 通过突变表型推断
23129809 MGI
acts upstream of or within placenta blood vessel development IMP
IMP: 通过突变表型推断
23129809 MGI
acts upstream of or within stem cell population maintenance IMP
IMP: 通过突变表型推断
18448678 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SWI/SNF complex IDA
IDA: 通过直接分析推断
11318604 MGI
part of SWI/SNF superfamily-type complex IDA
IDA: 通过直接分析推断
12368262 MGI
located in chromatin IDA
IDA: 通过直接分析推断
23129809 MGI
part of nBAF complex IDA
IDA: 通过直接分析推断
17640523 MGI
part of npBAF complex IDA
IDA: 通过直接分析推断
17640523 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

AT-rich interactive domain-containing protein 1A

ARID domain-containing protein 1A

AT rich interactive domain 1A (Swi1 like)

BRG1-associated factor 250a

SWI-like protein

SWI/SNF complex protein p270

SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1

osa

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114268 BRD-K98645985 Inhibitor 98.67% 否
HY-RS00966 ARID1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17472 Arid1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23930 Arid1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arid1a NCBI NCBI:8289
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