2. Gene
  3. Cers1 - ceramide synthase 1 Gene

Cers1 - ceramide synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: to; Lass1; Uog-1

基因 ID: 93898 | 基因类型: protein coding

关于 Cers1

功能概要

This gene encodes a ceramide synthase enzyme, which catalyzes the synthesis of ceramide, the hydrophobic moiety of sphingolipids. The encoded enzyme synthesizes 18-carbon (C18) ceramide in brain neurons. Mice lacking a functional copy of this gene exhibit impaired cerebellar development, locomotion and motor coordination. This protein is transcribed from a bicistronic mRNA, which also encodes Growth Differentiation Factor 1. [provided by RefSeq, Jul 2016]

Cers1 基因产物(1)

mRNA Protein Name
NM_138647.3 NP_619588.1 ceramide synthase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acyltransferase activity IMP
IMP: 通过突变表型推断
21625621 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
26620563 MGI
enables sphingosine N-acyltransferase activity IDA
IDA: 通过直接分析推断
16951403 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within brain development IMP
IMP: 通过突变表型推断
15248193 MGI
involved in ceramide biosynthetic process IDA
IDA: 通过直接分析推断
16951403 MGI
involved in ceramide biosynthetic process IMP
IMP: 通过突变表型推断
21625621 MGI
involved in negative regulation of D-glucose import IMP
IMP: 通过突变表型推断
30605666 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
16951403 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ceramide synthase 1

LAG1 homolog, ceramide synthase 1

LAG1 longevity assurance homolog 1

longevity assurance gene 1 protein homolog 1

longevity assurance homolog 1

protein UOG-1

sphingoid base N-stearoyltransferase CERS1

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-126015 P053 Inhibitor 97.0% 否
HY-120803 Mefluidide 99.81% 否
HY-146910S CER1 (d18:1/26:0/18:1)-d9 99.0% 否
HY-176568 LCL768 / 否
HY-N15835 CER1(d18:1/28:0/18:2) / 否
HY-RS02532 CER1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS02536 CERS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05349 GDF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-175198 Cs-2d Inhibitor / 否
HY-RS18128 Cer1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19995 Cers1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24602 Cer1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26499 Cers1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cers1 NCBI NCBI:10715
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