2. Gene
  3. LRRC4B - leucine rich repeat containing 4B Gene

LRRC4B - leucine rich repeat containing 4B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含富含亮氨酸重复序列 4B

种属: Homo sapiens

同用名: HSM; LRIG4; NGL-3

基因 ID: 94030 | 基因类型: protein coding

关于 LRRC4B

This gene has 4 transcripts (splice variants), 256 orthologues and 22 paralogues. Biased expression in brain (RPKM 11.1), endometrium (RPKM 2.3) and 4 other tissues.

功能概要

预测启用信号受体结合活性。预计参与突触组装和突触膜粘附的调节。预测位于小脑苔藓纤维和突触前膜。预计在谷氨酸能突触和质膜中活跃。预计是突触后密度膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable signaling receptor binding activity. Predicted to be involved in regulation of synapse assembly and synaptic membrane adhesion. Predicted to be located in cerebellar mossy fiber and presynaptic membrane. Predicted to be active in glutamatergic synapse and plasma membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRRC4B 基因产物(2)

mRNA Protein Name
NM_001080457.2 NP_001073926.1 leucine-rich repeat-containing protein 4B precursor
NM_001348568.1 NP_001335497.1 leucine-rich repeat-containing protein 4B precursor

LRRC4B 蛋白结构

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (57 - 85)

LRR_5

LRR_5: Leucine rich repeats (6 copies) (101 - 223)

LRR_1

LRR_1: Leucine Rich Repeat (230 - 252)

LRR_8

LRR_8: Leucine rich repeat (253 - 311)

I-set

I-set: Immunoglobulin I-set domain (364 - 453)

  • 0
  • 200
  • 400
  • 600
  • 713 a.a.
蛋白主名 其他名称

leucine-rich repeat-containing protein 4B

leucine-rich repeats and immunoglobulin-like domains 4

关联疾病

疾病名称 别名
Childhood Infratentorial Ependymoma

Pediatric Infratentorial Ependymoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07821 LRRC4B Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta LRRC4B VGNC VGNC:74350
Canis familiaris LRRC4B VGNC VGNC:42802
Bos taurus LRRC4B VGNC VGNC:31019
Mus musculus LRRC4B MGD MGI:3027390
Rattus norvegicus LRRC4B RGD RGD:1307121
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