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  3. Hydrocortisone buteprate

Hydrocortisone buteprate (Synonyms: Hydrocortisone probutate; HBP)

目录号: HY-106673 纯度: 99.80%
产品使用指南

Hydrocortisone buteprate (Hydrocortisone probutate) 是一种中等效力的非卤化氢化可的松双酯,对治疗炎症性皮肤疾病具有良好的利弊比。Hydrocortisone buteprate (Hydrocortisone probutate) 可作为 0.1% 乳膏或软膏配方提供。

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Hydrocortisone buteprate Chemical Structure

Hydrocortisone buteprate Chemical Structure

CAS No. : 72590-77-3

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Size Price Stock Quantity
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥550 In-stock
10 mg ¥500 In-stock
50 mg ¥1500 In-stock
100 mg ¥2600 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation[1].

Molecular Weight

488.61

Formula

C₂₈H₄₀O₇

CAS No.

72590-77-3

SMILES

CCC(OCC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@@]4(C(CC3)=CC(CC4)=O)C)([H])[C@@H](O)C2)([H])CC1)C)OC(CCC)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (511.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0466 mL 10.2331 mL 20.4662 mL
5 mM 0.4093 mL 2.0466 mL 4.0932 mL
10 mM 0.2047 mL 1.0233 mL 2.0466 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案,配制前请先配制澄清的储备液,再依次添加助溶剂 (为保证实验结果的可靠性,体内实验的工作
液,建议您现用现配,当天使用;澄清的储备液可以根据储存条件,适当保存;以下溶剂前的百分比是指该溶剂在您配制终溶液中的体积占比):

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (4.26 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (4.26 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Hydrocortisone buteprate
目录号:
HY-106673
需求量:

Hydrocortisone buteprate

Cat. No.: HY-106673