1. Metabolic Enzyme/Protease Neuronal Signaling
  2. Glucosidase Cholinesterase (ChE)
  3. Kaempferol-3,7-di-O-β-glucoside

Kaempferol-3,7-di-O-β-glucoside  (Synonyms: 山柰酚-3,7-双葡萄糖苷; Kaempferol 3,7-diglucoside)

目录号: HY-N8161
产品使用指南

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) 是一种黄酮醇,对 α-淀粉酶 (α-amylase)、α-葡萄糖苷酶 (α-glucosidase) 和乙酰胆碱酯酶 (Acetylcholinesterase) 具有酶抑制作用。Kaempferol-3,7-di-O-β-glucoside 保护分化神经元细胞 SH-SY5Y 免受 Amyloid β 肽诱导的损伤。Kaempferol-3,7-di-O-β-glucoside 具有用于研究阿尔茨海默氏症的潜力。

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Kaempferol-3,7-di-O-β-glucoside Chemical Structure

Kaempferol-3,7-di-O-β-glucoside Chemical Structure

CAS No. : 25615-14-9

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查看 Cholinesterase (ChE) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside), a flavonol, possesses enzyme inhibition property towards α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3,7-di-O-β-glucoside protects differentiating neuronal cells, SH-SY5Y from Amyloid β peptide-induced injury. Kaempferol-3,7-di-O-β-glucoside has the potential for Alzheimer's research[1].

体外研究
(In Vitro)

Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside; 0.1, 100 μM) has effective inhibition in Aβ1-42 fibril formation. Kaempferol-3,7-di-O-β-glucoside has less neurotoxicity on the cultured SH-SY5Y cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

610.52

Formula

C27H30O16

CAS 号
中文名称

山柰酚-3,7-双葡萄糖苷;山柰酚-3, 7-二-O -β-D-吡喃葡萄糖苷

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Kaempferol-3,7-di-O-β-glucoside 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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