1. Inhibitory Antibodies
  2. Lepunafusp alfa

Lepunafusp alfa  (Synonyms: JR-171)

目录号: HY-P99694

Lepunafusp alfa (JR-171) 是一种可穿透血脑屏障的融合蛋白,由 J-Brain Cargo 和 IDUA (一种溶酶体酶, α-L-艾杜糖苷酶) 组成。Lepunafusp alfa 可降低硫酸乙酰肝素 (HS) 和硫酸皮肤素 (DS) 的浓度。Lepunafusp alfa 可用于 I 型粘多糖贮积症的研究。

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Lepunafusp alfa Chemical Structure

Lepunafusp alfa Chemical Structure

CAS No. : 2396411-71-3

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生物活性

Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I[1][2].

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lepunafusp alfa
目录号:
HY-P99694
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