1. Anti-infection
  2. Bacterial
  3. LolCDE-IN-2

LolCDE-IN-2 

目录号: HY-130840
产品使用指南

LolCDE-IN-2 是有效的 Lol 蛋白 (LolCDE) 抑制剂。LolCDE-IN-2 抑制 E. coli MG1655 的 MIC 值为 2 μg/ml。 具有抗菌活性。

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LolCDE-IN-2 Chemical Structure

LolCDE-IN-2 Chemical Structure

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Description

LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 inhibits E. coli MG1655 with a MIC of 2 μg/ml. Antibacterial activity[1].

In Vitro

The P. aeruginosa ΔlolCDE::CTX-lolCDEE. colistrain becomes more susceptible to LolCDE-IN-2 (compound 2A) when either the MexAB-OprM efflux pump is lacking or the permeability of its OM is increased by the expression of the FpvA-ΔP protein; in each case, these strains show an MIC of 16 µg/ml[1].

Molecular Weight

367.40

Formula

C₂₂H₁₇N₅O

SMILES

C1(C2=NNC=C2C3=CC=NC=C3)=CC(OCC4=CN5C(C=C4)=NC=C5)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

LolCDE-IN-2BacterialLolCDEtransportsystemoutermembraneInhibitorinhibitorinhibit

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产品名称:
LolCDE-IN-2
目录号:
HY-130840
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