2. Antibody-drug Conjugate/ADC Related Cytoskeleton Cell Cycle/DNA Damage
  3. Drug-Linker Conjugates for ADC Microtubule/Tubulin
  4. MC-VC(S)-PABQ-Tubulysin M

MC-VC(S)-PABQ-Tubulysin M 是合成 ADC 的药物-linker 偶联物，由微管蛋白聚合抑制剂 Tubulysin M (一种 ADC Cytotoxin) (HY-N7053) 和 MC-VC(S)-PABQ (一种 ADC linker) 连接而成。MC-VC(S)-PABQ-Tubulysin M 对多药耐药性淋巴瘤细胞系和肿瘤有效。

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MC-VC(S)-PABQ-Tubulysin M Chemical Structure

MC-VC(S)-PABQ-Tubulysin M Chemical Structure

CAS No. : 2055896-86-9

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MC-VC(S)-PABQ-Tubulysin M 相关抗体

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查看 Drug-Linker Conjugates for ADC 亚型特异性产品:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MC-VC(S)-PABQ-Tubulysin M is a synthetic ADC drug-linker conjugate composed of the tubulin polymerization inhibitor Tubulysin M (an ADC Cytotoxin) (HY-N7053) and MC-VC(S)- PABQ (an ADC linker) is connected. MC-VC(S)-PABQ-Tubulysin M is effective against multidrug-resistant lymphoma cell lines and tumors[1].

IC50 & Target[1]

Auristatin

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MC-VC(S)-PABQ-Tubulysin M 相关抗体:
分子量

1283.60

Formula

C66H96N11O13S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MC-VC(S)-PABQ-Tubulysin M 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC-VC(S)-PABQ-Tubulysin M2055896-86-9Drug-Linker Conjugates for ADCMicrotubule/TubulinInhibitorinhibitorinhibit

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