2. Academic Validation
  3. Novel alpha-amino-acid phenolic ester derivatives with intravenous anaesthetic activity

Novel alpha-amino-acid phenolic ester derivatives with intravenous anaesthetic activity

  • Bioorg Med Chem Lett. 2003 Mar 24;13(6):1107-10. doi: 10.1016/s0960-894x(03)00025-8.
Andrew Cooke 1,  Alison Anderson,  Jonathan Bennett,  Kirsteen Buchanan,  David Gemmell,  Niall Hamilton,  Maurice Maidment,  Petula McPhail,  Donald Stevenson,  Hardy Sundaram
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry, Organon Laboratories Ltd., Newhouse, Scotland, ML1 5SH, UK. a.cooke@organon.co.uk
PMID: 12643922 DOI: 10.1016/s0960-894x(03)00025-8
Abstract

A novel series of alpha-amino-acid phenolic ester derivatives containing sulphide, sulphoxide, sulphone, ester and amide side chains were prepared and shown to display potent intravenous anaesthetic activity.

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