2. Academic Validation
  3. A novel estrogen receptor ligand template

A novel estrogen receptor ligand template

  • Bioorg Med Chem Lett. 2003 Jun 2;13(11):1919-22. doi: 10.1016/s0960-894x(03)00307-x.
Robert Sibley 1,  Holia Hatoum-Mokdad,  Robert Schoenleber,  Laszlo Musza,  William Stirtan,  Diana Marrero,  William Carley,  Hong Xiao,  Jacques Dumas
Affiliations

Affiliation

  • 1 Bayer Research Center, Bayer Corporation, Pharmaceutical Division, 400 Morgan Lane, West Haven, CT 06516, USA. robert.sibley.b@bayer.com
PMID: 12749898 DOI: 10.1016/s0960-894x(03)00307-x
Abstract

Three synthetic routes towards a novel Estrogen receptor ligand template based on a rigid bicyclo-[3.3.1]-nonene core have been investigated. The prototype compound exhibits potent binding at the ERbeta receptor and promising Estrogen receptor subtype selectivity.

Figures
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z