1. Academic Validation
  2. Collagenase inhibitory quinic acid esters from Ipomoea pes-caprae

Collagenase inhibitory quinic acid esters from Ipomoea pes-caprae

  • J Nat Prod. 2005 May;68(5):794-6. doi: 10.1021/np0500631.
Fumihiro Teramachi 1 Takashi Koyano Thaworn Kowithayakorn Masahiko Hayashi Kanki Komiyama Masami Ishibashi
Affiliations

Affiliation

  • 1 Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.
Abstract

Two new quinic acid esters (1 and 2) were isolated from the extract of Ipomoea pes-caprae together with six known quinic acid esters (3-8). The structures of compounds 1 and 2 were elucidated by spectroscopic data interpretation. These new compounds exhibited collagenase inhibitory activity and showed almost no cytotoxicity.

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