2. Academic Validation
  3. Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,)

Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,)

  • J Nat Prod. 2008 Mar;71(3):438-44. doi: 10.1021/np700738k.
George R Pettit 1,  Fiona Hogan,  Jun-Ping Xu,  Rui Tan,  Toshihiko Nogawa,  Zbigniew Cichacz,  Robin K Pettit,  Jiang Du,  Qing-Hua Ye,  Gordon M Cragg,  Cherry L Herald,  Michael S Hoard,  Animesh Goswami,  Justin Searcy,  Larry Tackett,  Dennis L Doubek,  Lee Williams,  John N A Hooper,  Jean M Schmidt,  Jean-Charles Chapuis,  Denise N Tackett,  Felicia Craciunescu
Affiliations

Affiliation

  • 1 Department of Chemstry and Biochemistry, Arizona State University, Tempe, Arizona 85287-2404, USA. bpettit@asu.edu
PMID: 18327911 DOI: 10.1021/np700738k
Abstract

Bioassay-guided fractionation of extracts of various Plants, marine organisms, and Microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable Cancer cell growth inhibitors including majusculamide C ( 1), axinastatin 5 ( 5), bengazoles A ( 6), B ( 7), and E ( 8), manzamine A ( 10), jaspamide ( 11), and neoechinulin A ( 19) has been summarized.

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