1. Academic Validation
  2. Chemical constituents of the stem bark of Morus cathayana

Chemical constituents of the stem bark of Morus cathayana

  • J Asian Nat Prod Res. 2010 Jun;12(6):505-15. doi: 10.1080/10286020.2010.489817.
Gang Ni 1 Qing-Jian Zhang Ying-Hong Wang Ruo-Yun Chen Zhong-Fei Zheng De-Quan Yu
Affiliations

Affiliation

  • 1 The Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Peking Union Medical College, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Abstract

Phytochemical investigation of the stem bark of Morus cathayana led to the isolation and identification of six new compounds, cathayanons F-J (1-5) and cathayanin A (6), and two known compounds, cathayanins B-C (7-8). Their structures were elucidated by spectroscopic methods. Compounds 1, 2, 3, 5, and 7 exhibited weak activities against five human Cancer cell lines, with IC(50) values ranging from 4.7 to 9.8 microg/ml.

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