2. Academic Validation
  3. Plant anticancer agents. XXVI. Constituents of Peddiea fischeri

Plant anticancer agents. XXVI. Constituents of Peddiea fischeri

  • J Nat Prod. 1983 Mar-Apr;46(2):248-50. doi: 10.1021/np50026a020.
S S Handa,  A D Kinghorn,  G A Cordell,  N R Farnsworth
PMID: 6875580 DOI: 10.1021/np50026a020
Abstract

The in vitro P-388 lymphocytic leukemia activity of the chloroform-soluble fraction of the roots of Peddiea fischeri (Thymelaceaceae) was found to be due principally to the quinone 2,6-dimethoxybenzoquinone (2,6-DMBQ), and to a lesser extent the two Coumarins daphnoretin and umbelliferone. This is the first report of the occurrence of 2,6-DMBQ in the family Thymelaeaceae. The occurrence of 2,6-DMBQ in higher Plants is reviewed.

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