1. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Cannabinoid Receptor Endogenous Metabolite
  3. Mead ethanolamide

Mead ethanolamide 是一种内源性大麻素受体(cannabinoid receptor)激动剂,对 CB1CB2Kd 值分别为 753 nM 和 1810 nM。

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Mead ethanolamide Chemical Structure

Mead ethanolamide Chemical Structure

CAS No. : 169232-04-6

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生物活性

Mead ethanolamide is an endogenous cannabinoid receptor agonist with Kd values of 753 nM and 1810 nM against CB1 and CB2, respectively[1].

IC50 & Target

CB1

753 nM (Kd)

CB2

1810 nM (Kd)

体外研究
(In Vitro)

Mead ethanolamide inhibits cAMP accumulation in CHO-hCB1 and CHO-hCB2 cells with IC50s of 431 nM and 156 nM, respectively[1].
Mead ethanolamide (1-1000 nM) inhibits N-type calcium currents in a concentration-dependent manner. Inhibition was halfmaximal at a Mead ethanolamide concentration of 124 ± 19 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

349.55

Formula

C22H39NO2

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Mead ethanolamide
目录号:
HY-134615
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