1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. Minoxidil-d10

Minoxidil-d10  (Synonyms: 米诺地尔-d10)

目录号: HY-23196S 纯度: 99.70%
COA 产品使用指南

Minoxidil-d10 是 Minoxidil 的氘代物。Minoxidil (U10858) 是一种是 ATP 敏感的钾通道 (KATP) 开放剂,是有效的口服降压药和外周血管舒张药,可促进血管扩张并促进头发的生长。Minoxidil 还是一种大豆脂氧合酶的有效抑制剂,其 IC50 值为 20 μM。

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Minoxidil-d<sub>10</sub> Chemical Structure

Minoxidil-d10 Chemical Structure

CAS No. : 1020718-66-4

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  • 生物活性

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  • 参考文献

生物活性

Minoxidil-d10 (U10858-d10) is the deuterium labeled Minoxidil. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

219.31

Formula

C9H5D10N5O

CAS 号
性状

固体

颜色

White to off-white

中文名称

米诺地尔-d10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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