2. Cytoskeleton
  3. Myosin
  4. MPH-220

MPH-220 是一种选择性的、具有口服活性的骨骼肌 myosin-2 抑制剂。MPH-220 可使肌肉放松。MPH-220 是一种抗痉挛剂，可用于痉挛和肌肉僵硬的研究。

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MPH-220 Chemical Structure

MPH-220 Chemical Structure

CAS No. : 2649776-79-2

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规格 价格 是否有货 数量
1 mg ￥2040
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5 mg ￥5100
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10 mg ￥8100
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Other Forms of MPH-220:

MPH-220 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness[1].

体外研究
(In Vitro)

MPH-220 (0-50 µM) 抑制人肌肉肌球蛋白样品中肌动蛋白激活的 ATP 酶活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MPH-220 相关抗体:
体内研究
(In Vivo)

MPH-220 (25-30 mg/kg，腹腔注射或口服灌胃) 可降低麻醉大鼠的骨骼肌力量，而不会影响心血管[1]。
MPH-220 (15 mg/kg，口服) 改善脑损伤大鼠的步态功能[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Anesthetized rats[1]
Dosage: 25-30 mg/kg
Administration: Intraperitoneal injection (i.p.) or oral gavage
Result: Reduced skeletal muscle force.
Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.
分子量

383.46

Formula

C20H21N3O3S
CAS 号
性状

固体

颜色

Orange to red

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

MPH-220 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MPH-2202649776-79-2MPH220MPH 220Myosinmuscle myosinanti-spasticmuscle relaxationspasticitystiffnessATPaseActinInhibitorinhibitorinhibit

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目录号：
HY-148516
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