2. Anti-infection
  3. SARS-CoV
  4. Narsoplimab

Narsoplimab  (Synonyms: OMS 721; Anti-MASP2 Reference Antibody (narsoplimab))

目录号: HY-P99376 纯度: ≥95.0%
COA

摩尔计算器

Narsoplimab (OMS 721) 是一种高亲和力的全人免疫球蛋白γ 4 (IgG4) 单克隆抗体，可结合 MASP-2 并阻断凝集素通路激活。Narsoplimab 可用于造血干细胞移植和 SARS-CoV-2 的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

Narsoplimab Chemical Structure

Narsoplimab Chemical Structure

CAS No. : 2108782-45-0

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥4200
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

Narsoplimab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2[1].

体外研究
(In Vitro)

Narsoplimab (100 nM; 3 h; Vero E6 细胞和带有 SARS-CoV-2 的 Vero E6 细胞) 抑制了 N 蛋白增强的 MASP-2 沉积[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Narsoplimab 相关抗体:
体内研究
(In Vivo)

Narsoplimab (10 mg/kg; i.v.; WT and Masp2-/- (KO) mice) 降低了小鼠淋巴细胞百分比 (Lym%)，增加了中性粒细胞百分比 (Neu%)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: WT and Masp2-/- (KO) mice (C57BL/6N, female, 12-15 weeks old)[1]
Dosage: 10 mg/kg
Administration: Intravenous injection
Result: Decreased percentage of lymphocytes (Lym%) and an increased percentage of neutrophils (Neu%).
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Narsoplimab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Narsoplimab2108782-45-0OMS 721 Anti-MASP2 Reference Antibody (narsoplimab)OMS721OMS-721SARS-CoVSARS coronavirusmonoclonal antibodylectin pathwayhematopoietic stem-cell transplantationSARS-CoV-2N proteinVero E6Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Narsoplimab
目录号：
HY-P99376
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z