1. Anti-infection
  2. Antibiotic
    Bacterial
  3. Nifurpirinol

Nifurpirinol (Synonyms: P-7138)

目录号: HY-135470
产品使用指南

Nifurpirinol (P-7138) 是一种硝基芳香抗生素 (antibiotic),是细菌硝基还原酶 (NTR) 的底物。与甲硝唑相比,Nifurpirinol 是一种更有效的 prodrug,可在表达硝基还原酶的转基因模型中诱导细胞消融。

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Nifurpirinol Chemical Structure

Nifurpirinol Chemical Structure

CAS No. : 13411-16-0

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Description

Nifurpirinol (P-7138) is a nitroaromatic antibiotic and acts as a novel substrate for the bacterial nitroreductase (NTR) enzyme. Nifurpirinol is a more potent prodrug compared to Metronidazole to trigger cell-ablation in nitroreductase expressing transgenic models[1].

IC50 & Target

IC50: bacterial nitroreductase (NTR) enzyme[1]

Molecular Weight

246.22

Formula

C₁₂H₁₀N₂O₄

CAS No.

13411-16-0

SMILES

OCC1=NC(/C=C/C2=CC=C([N+]([O-])=O)O2)=CC=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NifurpirinolP-7138P7138P 7138AntibioticBacterialnitroaromaticantibioticcell-ablationnitroreductaseNTR enzymeInhibitorinhibitorinhibit

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产品名称:
Nifurpirinol
目录号:
HY-135470
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